MOTS-c is a mitochondrial-derived peptide that has gained attention in scientific research for its potential role in metabolism and age-related diseases. It is a short peptide encoded within the mitochondrial genome. MOTS-c has been shown to have various metabolic functions, including the regulation of metabolic homeostasis and the enhancement of glucose utilization, which could be beneficial in conditions like obesity and type 2 diabetes. Additionally, it has been observed to mimic the effects of exercise by improving physical performance and increasing fat metabolism in animal models. The peptide appears to function by activating AMP-activated protein kinase (AMPK), an enzyme that plays a key role in cellular energy homeostasis. Through the activation of AMPK, MOTS-c may promote the use of fatty acids for energy and improve insulin sensitivity.

This peptide comes in lyophilized vials.

Amount in vial: 10mg

Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
Molecular Weight: 2174.64 g/mol
CAS Number: 1627580-64-6
PubChem CID: 255386757